music

When Paul McCartney wrote “Get Back,” he never would have predicted how useful or relevant the song would become for music therapists.

The song’s refrain—“Get back to where you once belonged”—might as well be a therapist encouraging a dementia patient to recall a distant memory. In new research, Psyche Loui, an associate professor of music, is attempting to do exactly that.

Loui found that for older adults who listened to some of their favorite music, including The Beatles, connectivity in the brain increased. Specifically, Loui—and her multi-disciplinary team of music therapists, neurologists and geriatric psychiatrists—discovered that music bridged the gap between the brain’s auditory system and reward system, the area that governs motivation.

“There’s something about music that is this functional connectivity between the auditory and reward system, and that’s why music is so special and able to tap into these seemingly very general cognitive functions that are suddenly very engaged in folks with dementia who are hearing music,” said Loui, who directs the Music Imaging and Neural Dynamics Lab, and whose paper was published in Nature’s Scientific Reports.

The original idea for this research came out of Loui’s own experiences playing music in nursing homes. She recalled how people who couldn’t finish a sentence or thought would suddenly harmonize and sing along to a song she was playing.

“[Music] seems to engage the brain in this way that’s different than everything else,” Loui said.

The researchers had a group of older adults between the ages of 54 and 89 from the Boston area listen to a playlist for an hour every day for eight weeks and journal about their response to the music afterward.

Loui and the team would scan the participants’ brains before and after listening in order to measure their neurological response.

Playlists were highly personalized and featured a combination of the participants’ self-selected songs, which ranged from The Beatles to Bruce Springsteen, and a preselected mix of classical pieces, pop and rock songs and new compositions created by Hubert Ho, an associate teaching professor of music at Northeastern. Participants would then rate each song based on how much they liked it and how familiar it was.

“The most important lesson that we learned from the music therapist was that there is no one-size-fits-all for what kind of music works best,” Loui said.

What the researchers found was striking: music was essentially creating a channel directly between the auditory center and the medial prefrontal cortex, the brain’s reward center and one of the areas to lose its activity and functional connectivity in aging adults, especially in folks with dementia, Loui said.

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